Package: ofGEM 1.0

ofGEM: A Meta-Analysis Approach with Filtering for Identifying Gene-Level Gene-Environment Interactions with Genetic Association Data

Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data, proposed by Wang et al. (2018) <doi:10.1002/gepi.22115>. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.

Authors:Jiebiao Wang, Qianying Liu and Lin S. Chen

ofGEM_1.0.tar.gz
ofGEM_1.0.zip(r-4.5)ofGEM_1.0.zip(r-4.4)ofGEM_1.0.zip(r-4.3)
ofGEM_1.0.tgz(r-4.4-any)ofGEM_1.0.tgz(r-4.3-any)
ofGEM_1.0.tar.gz(r-4.5-noble)ofGEM_1.0.tar.gz(r-4.4-noble)
ofGEM_1.0.tgz(r-4.4-emscripten)ofGEM_1.0.tgz(r-4.3-emscripten)
ofGEM.pdf |ofGEM.html
ofGEM/json (API)

# Install 'ofGEM' in R:
install.packages('ofGEM', repos = c('https://randel.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/randel/ofgem/issues

Datasets:

On CRAN:

3.18 score 3 stars 3 scripts 137 downloads 2 exports 6 dependencies

Last updated 6 years agofrom:8d3618722d. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 17 2024
R-4.5-winOKNov 17 2024
R-4.5-linuxOKNov 17 2024
R-4.4-winOKNov 17 2024
R-4.4-macOKNov 17 2024
R-4.3-winOKNov 17 2024
R-4.3-macOKNov 17 2024

Exports:forest_plotofGEM

Dependencies:abindbackportscheckmateCompQuadFormforestplotMASS