Package: ofGEM 1.0
ofGEM: A Meta-Analysis Approach with Filtering for Identifying Gene-Level Gene-Environment Interactions with Genetic Association Data
Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data, proposed by Wang et al. (2018) <doi:10.1002/gepi.22115>. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.
Authors:
ofGEM_1.0.tar.gz
ofGEM_1.0.zip(r-4.5)ofGEM_1.0.zip(r-4.4)ofGEM_1.0.zip(r-4.3)
ofGEM_1.0.tgz(r-4.5-any)ofGEM_1.0.tgz(r-4.4-any)ofGEM_1.0.tgz(r-4.3-any)
ofGEM_1.0.tar.gz(r-4.5-noble)ofGEM_1.0.tar.gz(r-4.4-noble)
ofGEM_1.0.tgz(r-4.4-emscripten)ofGEM_1.0.tgz(r-4.3-emscripten)
ofGEM.pdf |ofGEM.html✨
ofGEM/json (API)
| # Install 'ofGEM' in R: |
| install.packages('ofGEM', repos = c('https://randel.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/randel/ofgem/issues
- sim_dat - A simulated data example
Last updated 7 years agofrom:8d3618722d. Checks:8 OK. Indexed: yes.
| Target | Result | Latest binary |
|---|---|---|
| Doc / Vignettes | OK | Feb 15 2025 |
| R-4.5-win | OK | Feb 15 2025 |
| R-4.5-mac | OK | Feb 15 2025 |
| R-4.5-linux | OK | Feb 15 2025 |
| R-4.4-win | OK | Feb 15 2025 |
| R-4.4-mac | OK | Feb 15 2025 |
| R-4.3-win | OK | Feb 15 2025 |
| R-4.3-mac | OK | Feb 15 2025 |
Exports:forest_plotofGEM
Dependencies:abindbackportscheckmateCompQuadFormforestplotMASS
