Package: GMAC 3.1
GMAC: Genomic Mediation Analysis with Adaptive Confounding Adjustment
Performs genomic mediation analysis with adaptive confounding adjustment (GMAC) proposed by Yang et al. (2017) <doi:10.1101/078683>. It implements large scale mediation analysis and adaptively selects potential confounding variables to adjust for each mediation test from a pool of candidate confounders. The package is tailored for but not limited to genomic mediation analysis (e.g., cis-gene mediating trans-gene regulation pattern where an eQTL, its cis-linking gene transcript, and its trans-gene transcript play the roles as treatment, mediator and the outcome, respectively), restricting to scenarios with the presence of cis-association (i.e., treatment-mediator association) and random eQTL (i.e., treatment).
Authors:
GMAC_3.1.tar.gz
GMAC_3.1.zip(r-4.5)GMAC_3.1.zip(r-4.4)GMAC_3.1.zip(r-4.3)
GMAC_3.1.tgz(r-4.4-any)GMAC_3.1.tgz(r-4.3-any)
GMAC_3.1.tar.gz(r-4.5-noble)GMAC_3.1.tar.gz(r-4.4-noble)
GMAC_3.1.tgz(r-4.4-emscripten)GMAC_3.1.tgz(r-4.3-emscripten)
GMAC.pdf |GMAC.html✨
GMAC/json (API)
| # Install 'GMAC' in R: |
| install.packages('GMAC', repos = c('https://randel.r-universe.dev', 'https://cloud.r-project.org')) |
- dat - Example data
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 3 years agofrom:7d08079f4b. Checks:OK: 7. Indexed: yes.
| Target | Result | Date |
|---|---|---|
| Doc / Vignettes | OK | Nov 01 2024 |
| R-4.5-win | OK | Nov 01 2024 |
| R-4.5-linux | OK | Nov 01 2024 |
| R-4.4-win | OK | Nov 01 2024 |
| R-4.4-mac | OK | Nov 01 2024 |
| R-4.3-win | OK | Nov 01 2024 |
| R-4.3-mac | OK | Nov 01 2024 |
Exports:gmac
Dependencies:
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Example data | dat |
| Genomic Mediation analysis with Adaptive Confounding adjustment | gmac |
